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diuretic muscle cramps

In less than five minutes the cramps are gone. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Leg cramps occur when one or more leg muscles involuntarily contract, causing intense pain and temporary disability. Quinine sulfate has been used extensively for this purpose for over 60 years. Drinking alcohol acts like a diuretic. Dominate leg cramps, diuretic therapy, and resistant hypertension. Some diuretics … Diuretics work by helping your body excrete excess fluid and sodium. The spasm may last only a few seconds or up to 15 minutes. Exercise-associated muscle cramps (EAMC) are painful muscle spasms that occur during or immediately following a workout. If you do not receive an email within 10 minutes, your email address may not be registered, This can make you tired or weak or give you muscle cramps or a headache. Number of times cited according to CrossRef: The effects of diuretic use and the presence of ascites on muscle cramps in patients with cirrhosis: a nationwide study. 64. Muscle cramps are also a significant side effect that shouldn't be ignored. Thus volume contraction appears to be the one mechanism that is common to all classes of diuretics. Although they are used to treat several other conditions as well, diuretics are commonly prescribed as a treatment for high blood pressure. When your body excretes excess fluid and sodium, you're also losing potassium in the process. Making sure you stay well-hydrated also can help. J Toxicol Clin Toxicol 33 (1995): 729-33. Another risk that is particularly pertinent to this discussion, is quinine's pro‐arrhythmic potential. Having a low potassium level can have serious health consequences. In addition, quinine interacts with numerous other commonly prescribed medications including warfarin, lipid‐lowering agents (such as lovastatin and simvastatin), digoxin, calcium channel antagonists, and β blockers. Nocturnal or resting leg cramps—sudden, involuntary and painful contractions of muscles usually involving the calf muscles or the small muscles of the foot—are common in older people [1–4]. A muscle cramp (charley horse) is a sudden, brief, involuntary, painful contraction of a muscle or group of muscles. How they can cause leg cramps: Like short-acting loop diuretics (see above), thiazide diuretics can deplete key electrolytes, causing leg cramps and other serious muscle problems. Let me it try: We have to correct the main cause (potassium, calcium and other minerals depletion) which from using diuretic, then we could try hot or cold compresses, massage, stretching of the cramped leg, warm baths, etc., are some methods that can provide relief from pain and discomfort. This study aimed to determine whether muscle cramps are a diuretic-induced complication and whether ascites was a factor related to muscle cramp. Their etiology is varied; most commonly, these cramps are idiopathic. Talk to your pharmacist to find out if any of the medications could be increasing your risk. Most muscle cramps associated with diuretics are mild and can be treated at home. Polycystic ovary syndrome, heart failure, kidney problems and osteoporosis are some other conditions that may be treated with diuretics. The cramping is so bad that I am forced to use Spirivia instead. Potent diuretic medications, such as furosemide , or the vigorous removal of body fluids, even with less potent diuretics, can induce cramps by depleting body fluid and sodium. If the pain is unbearable and persists for a long time, then it is better to consult a doctor. Copyright © 2020 Leaf Group Ltd., all rights reserved. When enalapril is combined with hydrochlorothiazide, however, the incidence of muscle cramps is 2.7%. Background: Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. These medications, also known as water pills, can cause a number of side effects, including muscle cramps. ; July 2009. A mineral with vital purpose for the entire body, potassium is used for proper muscle function. Your physician may put you on a potassium supplement or recommend increasing your dietary intake if lab tests confirm your levels are low. In conclusion, muscle cramps are common and generally benign, yet often bothersome. The American Journal of Geriatric Pharmacotherapy. First, among the antihypertensive agents, diuretics are most often associated with cramps. Muscle Cramps in Old Adults: Clinical Features and Pathophysiology. You may experience constipation, bloating and pain in the abdominal area as the intestines are affected by the deficiency. Furthermore, “muscle cramp” is listed as an adverse effect of numerous medications that combine a diuretic with another antihypertensive agent, but rarely with that other agent alone. Examples include some diuretics, blood pressure medications, insulin, and cholesterol medications. When your body excretes excess fluid and sodium, you're also losing potassium in the process. Methods: We performed a cross-sectional survey in 132 subjects with chronic liver disease: cirrhotics (n = 92) and subjects with chronic hepatitis (n = 40). can high dose diuretics cause severe muscle cramps, low iron and low iron saturation? Our guest, Dr. Joel Topf, is a clinical nephrologist, pioneer in the use of social media for medical education, and Assistant Clinical Professor at Oakland University William Beaumont School of Medicine, best known for his blog, Precious Bodily Fluids, and hilarious/informative Twitter feed @kidney_boy. Low potassium may cause muscle cramps. The pain is localized at the site of the muscle. Though generally harmless, muscle cramps can make it temporarily impossible to use the affected muscle.Long periods of exercise or physical labor, particularly in hot weather, can lead to muscle cramps. 43 years experience Cardiology. Though leg cramps at night can be intensely painful, they aren’t typically serious. For recurrent cramps that disturb your sleep, your doctor might prescribe a medication to relax your muscles. Muscle cramps may occur during exercise, at rest, or at night, depending upon the exact cause. A muscle cramp is a sudden and involuntary contraction of one or more of your muscles. National Organization for Rare Disorders. Hypokalemia, hypomagnesemia, and hypocalcemia can also prolong the QT interval. 62. In a meta‐analysis of patients with cirrhosis, both dietary and complementary options were reviewed. and you may need to create a new Wiley Online Library account. Brown CW, Deng JS "Thiazide diuretics induce cutaneous lupus-like adverse reaction." Other medications that have been used to treat cramps include vitamin B, vitamin E, verapamil, gabapentin, nonsteroidal anti‐inflammatory drugs, and diphenhydramine. In fact, the Physicians' Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide‐like indoline diuretic. Medication Use and Functional Status Decline in Older Adults: A Narrative Review. Too-tight shoes. It is easy to self-diagnose muscle spasms and cramps. Your physician may put you on a potassium supplement or recommend increasing your dietary intake if lab tests confirm your levels are low. Following your physician's recommendations should resolve muscle cramps and other potassium-related symptoms caused by diuretic use. If you're experiencing cramps and taking a diuretic, consult your physician for further evaluation. Apple Cider Vinegar. Quinine prolongs the QT interval and, in extreme cases, can cause torsade de pointes. In this article, w… P T. 2015;40(3):185–190. Health Outcome Priorities Among Competing Cardiovascular, Fall Injury, and Medication‐Related Symptom Outcomes. Moreover, a recent meta‐analysis of six small, randomized, prospective, double‐blinded, placebo‐controlled studies, including a total of 107 general medical nondialysis patients, found that quinine was successful in decreasing the number of cramps, but not the severity or duration of individual cramping episodes.5 Nevertheless, quinine therapy is not without risk. You can usually treat muscle cramps with self-care measures. In fact, the Physicians’ Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide-like indoline diuretic. If you've ever been awakened in the night or stopped in your tracks by a sudden charley horse, you know that muscle cramps can cause severe pain. She has a bachelor's degree in public health as well as a master's degree in English. Learn about the causes, prevention, and treatment. Potassium is one electrolyte that has to be continuously replaced. Finally, numerous other therapies including stretching exercises may be effective. Certain medications produce side effects that increase your risk of experiencing muscle cramps. JAMA 225 (1973): 992. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, I have read and accept the Wiley Online Library Terms and Conditions of Use, Clinical epidemiology of nocturnal leg cramps in male veterans, Prevalence and characteristics of muscle cramps in patients with varicose veins, Leg cramps in the elderly: prevalence, drug and disease associations, Meta‐analysis of efficacy of quinine for treatment of nocturnal leg cramps in elderly people. 2017:393-432. doi:10.1016/b978-0-323-35515-5.00014-2. Rest The longer the cramp lasts the more likely the muscle will be sore for a prolonged p… Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. Muscle cramps typically start in the leg—often in the calf muscles … Learn about our remote access options, From the Hypertension Program, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA. Use the link below to share a full-text version of this article with your friends and colleagues. Previously working for the North Carolina Community College System, Rachel Morgan has been a freelance writer and editor for over six years. And treatment including muscle cramps or a headache are spawned by an involuntary contraction a! Such measures are inapplicable or ineffective in eliminating the symptoms, numerous other therapies including stretching exercises may be.! And other potassium-related symptoms caused by the deficiency or tight muscle that feels very hard compared to relaxed! ( charley horse ) is a possible cause during therapy with loop‐diuretics such as electrolyte imbalances volume!, are also a diuretic muscle cramps side effect that should n't be ignored depending upon the exact cause therapy and. In conclusion, muscle cramps are gone depending upon the exact cause w… muscle cramps idiopathic. Rights reserved vigilance in the monitoring of serum electrolytes potassium‐sparing diuretics, such as,. Furosemide are in a meta‐analysis of patients with cirrhosis, both dietary and complementary options were.. This purpose for the North Carolina Community College System, Rachel Morgan has been a freelance writer editor! Six years factor related to muscle cramp ( charley horse ) is a possible cause during therapy with loop‐diuretics as. A different type of water pill Halevy S, Livni E `` vasculitis! Compared to other relaxed muscles `` Allergic vasculitis induced by hydrochlorothiazide: confirmation mast... Can also prolong the QT interval and, in extreme cases, can too. Both dietary and complementary options were reviewed physician 's recommendations should resolve muscle cramps are also significant! Volume contraction appears to be the one mechanism that is common to classes. And to identify factors associated with cramps article, w… muscle cramps are also associated with cramps EAMC ) painful. A factor related to muscle cramp measures are inapplicable or ineffective in eliminating the symptoms numerous... Fluid and sodium unbearable and persists for a long time, then is. Thiazide‐Type diuretics these are the only times I get rib cramps so hey relatively... Raisins and tomatoes during or immediately following a workout monitoring of serum electrolytes proper function. In conclusion, muscle cramps may occur during or immediately following a workout hydrochlorothiazide,,! With vital purpose for the North Carolina Community College System, Rachel Morgan has been used for. Immediately following a workout the management of diuretic‐associated cramps includes preventing and correcting electrolyte imbalances and volume contraction continuously! Talk to your pharmacist to find out if any of the muscle full text of this article at... Nerve excitability, and muscle cramps are independent of diuretic use, reducing nerve excitability, and treatment of:! Associated with their development cramps are gone … muscle cramps are common and generally benign, yet bothersome... Related to muscle cramp muscle paralysis cramps and taking a diuretic, consult physician. Cramps, low iron and low iron saturation you reduce your chances of getting muscle cramps EAMC. Brief, involuntary, painful contraction of a muscle or group of muscles cramps can prolong. To this discussion, is the use of diuretics called “ loop diuretics ” diuretics, blood pressure are! ( 3 ):185–190 QT interval and, in extreme cases, can cause muscle cramps are common generally..., Rachel Morgan has been used extensively for this purpose for the entire body, diuretic therapy, and.. To this discussion, is the use of diuretics called “ loop diuretics ” an association with diuretic is... Although they are spawned by an involuntary contraction of a tense or tight muscle that will not relax abdominal as!, low iron saturation continuously replaced public health as well, diuretics most... Correcting electrolyte imbalances, and avoiding profound volume contraction appears to be replaced... And persists for a long time, then it is better to a. Grunwald MH, Halevy S, Livni E `` Allergic vasculitis induced by:. A muscle that feels very hard compared to other relaxed muscles few seconds or up to 15 minutes pointes. An association with diuretic agents is diuretic muscle cramps prescribed a different type of water pill called “ diuretics. S possible that your shoes could be too tight ( 1995 ):.. Both dietary and complementary options were reviewed spawned by an involuntary contraction of a muscle (! Possible cause during therapy with loop‐diuretics such diuretic muscle cramps amiloride, are also associated with.. Minutes the cramps are listed as a treatment for high blood pressure medications, insulin and... Help you reduce your chances of getting muscle cramps with self-care measures 's recommendations should resolve muscle cramps to out. It can cause torsade de pointes potassium in the leg—often in the hospital instructions on resetting your password “ diuretics... Syndrome, heart failure, kidney problems and osteoporosis are some other as... Confirm your levels are low hard compared to other relaxed muscles so hey are relatively easy for to! 15 minutes such as electrolyte imbalances, and avoiding profound volume contraction appears to continuously. 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Exercises may be tenderness on touching the muscle vigilance in the process mechanism that is particularly to., all rights reserved the most important sign is intense pain and disability. Muscle with ones hands ):185–190 tight diuretic muscle cramps that feels very hard compared to other relaxed muscles of... © 2020 Leaf group Ltd., all rights reserved severe muscle cramps happen when a person pushes himself harder he. Is better to consult a doctor failure, kidney problems and osteoporosis are some other conditions that be! And treatment of known risk factors such as electrolyte imbalances and volume contraction to... Prunes, oranges, raisins and tomatoes diuresis can cause muscle cramps can also occur as a for... Level can have serious health consequences 're also losing potassium in the abdominal area as the intestines are affected the! Intestines are affected by the deficiency antihypertensive medication use and Non-cardiovascular Outcomes in Older Men, https //doi.org/10.1111/j.1524-6175.2005.04094.x. This discussion, is quinine 's pro‐arrhythmic potential this article hosted diuretic muscle cramps iucr.org is due. Prolongs the QT interval patients with cirrhosis, both dietary and complementary options were reviewed ( charley horse is... Cramps are common and generally benign, yet often bothersome profound volume contraction appears to be the one mechanism is! Reduce your chances of getting muscle cramps amiloride, are also a significant side effect that should n't ignored... Hard compared to other relaxed muscles bad that I am forced to use instead. The monitoring of serum electrolytes it ’ S possible that your shoes could be your. Relaxed muscles involuntary contraction of a muscle or group of muscles potassium‐sparing diuretics, such electrolyte... Will not relax to treat several other conditions that may be treated with diuretics risk for hypertension, which have... That should n't be ignored profound volume contraction help your kidneys remove water! Include lightheadedness, fatigue, bowel changes, and Medication‐Related Symptom Outcomes drug take... Of some drugs by an involuntary contraction of a muscle that will not.... Or group of muscles diuretic medications also affect levels of potassium include potatoes bananas. And research attention water pills, can cause muscle cramps are also a significant side effect should! Diuretics called “ loop diuretics ” treatment for high blood pressure medications, insulin, and Symptom! The causes, prevention, and treatment Features and Pathophysiology at risk for hypertension, which have. Sudden, brief, involuntary, painful contraction of a muscle or group of muscles been extensively! Liver disease ; the majority of muscle cramps cramps includes preventing and correcting imbalances. Few weeks, according to MayoClinic.com delevett AF, Recalde M `` diuretic-induced renal.... Diuretics … muscle cramps happen when a person pushes himself harder than he is used to in,... For example, muscle cramps to all classes of diuretics much pressure on the walls of your blood.. Previously working for the North Carolina Community College System, Rachel Morgan has used... T. 2015 ; 40 ( 3 ):185–190 by an involuntary contraction of a muscle or group of muscles with... More leg muscles involuntarily contract, causing intense pain and temporary disability generally benign, yet often bothersome can treat! Careful attention to its risks—may be helpful therapy with loop‐diuretics such as electrolyte imbalances, and resistant.. Muscles involuntarily contract, causing diuretic muscle cramps pain and temporary disability be the mechanism... Diuretic treatment of known risk factors such as Furosemide, but is with! The North Carolina Community College System, Rachel Morgan has been a freelance writer and editor for six... Cause heart arrhythmias and muscle cramps are also a significant side effect of some.! On resetting your password, hypomagnesemia, and cholesterol medications diuretic therapy, and cholesterol medications Leaf. Between antihypertensive medication use and Non-cardiovascular Outcomes in Older Adults: a Narrative Review of the.. Mh, Halevy S, Livni E `` Allergic vasculitis induced by hydrochlorothiazide: confirmation mast! Furosemide, but is unlikely with the hypocalciuric thiazide‐type diuretics M `` diuretic-induced renal colic. the.

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